vol. 2025 · evidence-based · integrative medicine

Where naturopathic tradition meets clinical evidence.

peptides/metabolic/bioregulators/mitochondrial/anti-aging

Read the research →

Topics covered in this volume: peptides·metabolic·bioregulators·mitochondrial·anti-aging

CJC-1295 and Ipamorelin — the science behind GHRH and ghrelin receptor synergy

CJC-1295 and Ipamorelin act on different receptor classes — GHRH-R and the ghrelin receptor — to amplify the natural pulsatile growth hormone pulse. This article covers how the two mechanisms complement each other and why the combination produces cleaner GH release than either compound alone.

Epitalon and telomere biology — the tetrapeptide telomerase activator from the Khavinson program

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide derived from epithalamin that activates telomerase, extends telomere length in cell culture models, and modulates pineal melatonin secretion. This article covers the telomere shortening biology, the Khavinson research program, and what the preclinical data shows about cellular ageing mechanisms.

Research peptides: complete guide to mechanisms, categories, and evidence

A comprehensive reference covering all major categories of research peptides: tissue repair, cognitive enhancement, metabolic regulation, longevity, and mitochondrial function. Covers mechanisms, evidence quality, regulatory status, and cross-category comparisons.

Recent

CJC-1295 and Ipamorelin — the science behind GHRH and ghrelin receptor synergy

Mitochondrial peptides — an overview of the emerging mitokine class

Epitalon and telomere biology — the tetrapeptide telomerase activator from the Khavinson program

NAD+ and the sirtuin longevity pathway — why mitochondrial redox state governs ageing biology

Peptide bioregulators — the Khavinson framework for tissue-specific gene expression modulation

Research peptides: complete guide to mechanisms, categories, and evidence

Science without the marketing layer.

Every article is built from primary literature — clinical trials, meta-analyses, and peer-reviewed research. We translate the mechanism, not the marketing copy.