vol. 2025 · evidence-based · integrative medicine

Where naturopathic tradition meets clinical evidence.

peptides/metabolic/bioregulators/mitochondrial/anti-aging
Read the research →
Topics covered in this volume: peptides·metabolic·bioregulators·mitochondrial·anti-aging
Peptides
5 min read
CJC-1295 and Ipamorelin — the science behind GHRH and ghrelin receptor synergy
CJC-1295 and Ipamorelin act on different receptor classes — GHRH-R and the ghrelin receptor — to amplify the natural pulsatile growth hormone pulse. This article covers how the two mechanisms complement each other and why the combination produces cleaner GH release than either compound alone.
Bioregulators
Epitalon and telomere biology — the tetrapeptide telomerase activator from the Khavinson program
Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide derived from epithalamin that activates telomerase, extends telomere length in cell culture models, and modulates pineal melatonin secretion. This article covers the telomere shortening biology, the Khavinson research program, and what the preclinical data shows about cellular ageing mechanisms.
5 min read
Peptides
Research peptides: complete guide to mechanisms, categories, and evidence
A comprehensive reference covering all major categories of research peptides: tissue repair, cognitive enhancement, metabolic regulation, longevity, and mitochondrial function. Covers mechanisms, evidence quality, regulatory status, and cross-category comparisons.
6 min read
Recent
hormones
Hashimoto's Thyroiditis: A Naturopathic Guide to Root Causes and Therapeutic Protocols
May 2026
Metabolic
Mast Cell Activation Syndrome (MCAS): Naturopathic Assessment and Management
May 2026
Metabolic
GI-MAP Stool Test: A Naturopathic Clinician's Guide to Interpretation
May 2026
functional
Liver Detoxification Phases: The Evidence Behind Phase 1 and Phase 2 Biotransformation
May 2026
Metabolic
The Methylation Cycle: A Naturopathic Guide to MTHFR, Homocysteine, and One-Carbon Metabolism
May 2026
Mitochondrial
NMN vs NR: Comparing NAD+ Precursors for Longevity and Cellular Health
May 2026

Science without the marketing layer.

Every article is built from primary literature — clinical trials, meta-analyses, and peer-reviewed research. We translate the mechanism, not the marketing copy.