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Peptides

CJC-1295 and Ipamorelin — the science behind GHRH and ghrelin receptor synergy

CJC-1295 and Ipamorelin act on different receptor classes — GHRH-R and the ghrelin receptor — to amplify the natural pulsatile growth hormone pulse. This article covers how the two mechanisms complement each other and why the combination produces cleaner GH release than either compound alone.

5 min read

bioregulators

Epitalon and telomere biology — the tetrapeptide telomerase activator from the Khavinson program

Epitalon (Ala-Glu-Asp-Gly) is a synthetic tetrapeptide derived from epithalamin that activates telomerase, extends telomere length in cell culture models, and modulates pineal melatonin secretion. This article covers the telomere shortening biology, the Khavinson research program, and what the preclinical data shows about cellular ageing mechanisms.

6 min read

Peptides

IGF-1 and GH interpretation — why serum GH tells you nothing

Serum GH is useless for monitoring growth hormone status. IGF-1 is the 24-hour integrated signal that actually reflects GH output. Here's how to interpret it, age-adjust it, and use it to track peptide protocols.

9 min read