evidence-based · integrative research

Where naturopathic tradition meets clinical evidence.

Research-grade breakdowns of peptide science, bioregulators, mitochondrial biology, and metabolic interventions. Every claim traced back to the primary literature, no marketing copy.

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Peptides

The Australian Peptide Research Landscape 2026

A comprehensive reference mapping Australian peptide research in 2026: TGA regulatory framework, major peptide classes, research institutions, compounding rules, and 2024–26 policy shifts.

22 min read·Apr 30, 2026
What we cover

Five research lanes. One editorial standard.

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hormones
Graves' Disease and Hyperthyroidism: Naturopathic Evidence Beyond Antithyroid Drugs
An evidence-based naturopathic guide to Graves' disease and autoimmune hyperthyroidism: TSH-receptor antibody pathophysiology, why iodine and kelp must be avoided, the selenium RCT for Graves' orbitopathy, the L-carnitine trial evidence, and the honest limits of bugleweed.
Oct 8, 202612 min read
hormones
PMS and PMDD: What a New Supplement Trial Shows, and What the Stronger Evidence Actually Says
A double-blind trial of a ten-ingredient, manufacturer-funded herbal supplement for premenstrual syndrome reported modest benefits. This article reviews that trial honestly, including its funding and design limits, then compares it against the firmer, better-characterized evidence for Vitex agnus-castus, calcium, and vitamin B6.
Oct 1, 202613 min read
clinical
Curcumin for Depression: What a 2026 Meta-Analysis of 19 Trials Actually Shows
A 2026 systematic review and meta-analysis pooled 19 randomized controlled trials testing curcumin supplementation against placebo for depression and depressive symptoms. The pooled effect was statistically significant, but the authors' own sensitivity analysis found it fragile. This article reviews the numbers, the caveats, and what an honest reading means for naturopathic practice.
Sep 24, 20269 min read
autoimmune
Vitamin D3 for Autoimmune Disease: What a 2026 Meta-Analysis of 27 Trials Actually Shows
A 2026 meta-analysis pooled 27 randomized controlled trials (n=1864) testing vitamin D3 against placebo in people with autoimmune disease. This article reviews what improved, what did not move at all, and what that split means for naturopathic practice.
Sep 17, 20269 min read
Metabolic
PCOS: What a New Randomized Trial Shows About Combining Metformin, Inositol, and Diet
A 2026 randomized controlled trial tested metformin, inositol, calorie-restricted diet, and all three combined, head to head in 192 women with PCOS. This article reviews the trial design, results, and limitations, and what the findings mean for naturopathic PCOS protocols.
Sep 10, 20267 min read
Metabolic
Functional Medicine for Type 2 Diabetes: What a New Randomized Trial Shows
A Cleveland Clinic randomized pilot trial tested whether adding a full functional medicine program, diagnostic testing, elimination diet, and a targeted supplement stack, to usual care improved outcomes for insulin-treated type 2 diabetes. It did not. This article reviews the trial design, results, and what an honest reading means for naturopathic practice.
Sep 3, 202610 min read
Editorial method

Science without the marketing layer.

Every article is built from primary literature, clinical trials, meta-analyses, and peer-reviewed research. We translate the mechanism, not the marketing copy. When evidence is preliminary, conflicting, or absent, we say so explicitly.

Primary sourcesPubMed-indexed studies, clinical trials, systematic reviews.
No marketing copyNo sponsored content, no paid placement, no copy from supplement brands.
Corrections welcomeFactual corrections from clinicians and researchers are reviewed and applied openly.
Read our editorial standards